$50,000 for Clinical Trial at Miami Children’s Hospital
John Raghelb, M.D.
I Care I Cure’s funding facilitated the clinical trial for 10 children with recurrent brain cancer with an innovative and novel alternative method of giving chemotherapy directly to the site of the tumor. This study will determine if infusion of chemotherapeutic agents directly into brain fluid spaces is a safe and effective method of delivering chemotherapy treatment for children with recurrent malignant brain tumors.
$100,000* for Development of Targeted Leukemia Inhibitors Using Nanoparticle Delivery
Lucio Castilla, PhD - University of Massachusetts Medical School,
Research using the targeted therapy of soluble gold nanoparticles as inert and versatile scaffolds to deliver potent leukemia inhibitors aimed at eliminating cancer cells, while having a negligible impact in normal cells.
$100,000* for Targeted Inhibition of the DNA Damage Response Pathway: A Novel Intervention in the Treatment of Pediatric Leukemia
Andre Nessenzweig, PhD - National Cancer Institute
Research based on DNA damage response proteins to target therapeutic intervention as an inhibitor. These interventions are directed at specific cells, pathways or proteins that are indicative of heightened points of vulnerability in cancers, without the use of broad spectrum approaches.